Home Covid News and Updates Omicron sub-variant BA.2 harder to identify: WHO

Omicron sub-variant BA.2 harder to identify: WHO

by Vaishali Sharma

A World Health Organization expert stated on Thursday that the BA.2 sub-variant of Omicron has been discovered in five African nations, adding that she was concerned about the development since samples of BA.2 may not be recognised as a type of Omicron.

In nations like Denmark, the BA.2 sub-variant has begun to supplant Omicron’s more widespread “original” BA.1 version. According to another WHO expert, the data reveals no difference in illness severity.

“BA.2 … has been reported in five countries, that is Botswana, Kenya, Malawi, Senegal as well as South Africa,” Dr Nicksy Gumede-Moeletsi told an online media briefing. “We are very concerned,” she said, adding that BA.2 was proving hard to identify because it was not always picked up by the S-Gene Target Failure criterion, which is used to distinguish the original Omicron from other variants.

Gumede-Moeletsi said the WHO was working very closely with laboratories, asking them to forward samples that had come back without being flagged as Omicron for further analysis, in order to gain a more precise picture of the spread of BA.2.

The BA.1 version of Omicron has been somewhat easier to track than prior variants. That is because BA.1 is missing one of three target genes used in a common PCR test.

Cases showing this pattern were assumed by default to be caused by BA.1.BA.2, sometimes known as a “stealth” sub-variant, does not have the same missing target gene as the original Omicron variant.

Instead, scientists are monitoring it the same way they have prior variants, including Delta, by tracking the number of virus genomes submitted to public databases such as GISAID.

As with other variants, an infection with BA.2 can be detected by coronavirus home tests kits, though they cannot indicate which variant is responsible, experts said.


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