An 18-year-old female patient was successfully transplanted with allogeneic bone marrow-peripheral stem cells by specialists at ESIC Medical College and Super Speciality Hospital in Sanathnagar. On Wednesday, the woman was released from the hospital. This is the first time such a surgery has been carried out in an ESIC facility anywhere in the nation.
The infusion of healthy blood-forming stem cells from a matched donor into a patient to replace sick or damaged cells is known as bone marrow stem cell transplantation. Patients with leukaemia, lymphomas, aplastic anaemia, and immune deficiency diseases undergo this treatment.
There are two types of transplantations: autologous in which a person’s own stem cells are used, and allogeneic in which the cells are taken from a donor. The super speciality hospital’s doctors said that a dedicated medical and nursing team, advance planning and timing of the procedure are important in successful outcome of the allogeneic transplantations.
At this hospital in Hyderabad, Department of Transfusion Medicine and Haematology performed the procedure. The patient was diagnosed with severe aplastic anaemia with paroxysmal nocturnal haemoglobinuria [ PNH ] clone which made this transplant challenging. The peripheral blood stem cells were harvested from completely matched donor who is her sibling. She has recovered from the underlying condition.
“ESIC Hospital at Sanathnagar has plans to establish the full-fledged Bone Marrow Transplant facility along with transplantation immunology (HLA typing and CART cells) and Stem cell (Mesenchymal and Induced pluripotency stem cells) labs to give one point solution to all ESIC Medical College Hospitals. The facility will be useful for ESIC insured persons with haematological malignancies across the country,” said Prof Srinivas