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New study has shown relationship between prediabetes and chance of having heart attack

by Pragati Singh

Prediabetes appears to be a substantial independent risk factor for heart attacks, according to a new study presented at ENDO 2022, the Endocrine Society’s annual meeting.
Prediabetes is defined as blood glucose levels that are greater than usual but not high enough to be classified as diabetes. Diabetes is more likely in those who have prediabetes. While diabetes is known to cause serious health problems like heart attacks, strokes, and kidney problems, the link between prediabetes and heart problems has not been well established, according to study lead author Kavin Raj, M.D., of Saint Peter’s University Hospital/Rutgers Robert Wood Johnson Medical School in New Brunswick, N.J.

“Our study serves as a wake-up call to everyone to shift the focus from diabetes to prediabetes,” Raj added. “Based on our findings, we recommend everyone to adopt lifestyle changes, eat a nutritious diet, and exercise regularly for at least 150 minutes per week in patients with prediabetes to reduce the risk of heart attacks.”


The researchers examined data from 1.79 million hospitalizations of heart attack patients. One percent of these patients had prediabetes. After controlling for risk variables for heart disease such as age, gender, race, family history of heart disease, high blood pressure, high cholesterol, diabetes, smoking, and obesity, prediabetes was related with a 25% greater risk of a heart attack compared to people without prediabetes.

Those with prediabetes were also 45 percent more likely to have percutaneous intervention (a cardiac therapy to unblock clogged blood arteries) and nearly twice as likely to have heart bypass surgery.

“Our findings emphasise the need of early detection of prediabetes by screening and early management with lifestyle modifications and/or drugs to reduce the risk of cardiovascular events,” Raj added.

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