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delhi high court
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Delhi HC directs Delhi govt to bring forth any person overcharging O2 cylinders

by Medically Speaking Team
written by Medically Speaking Team

The Delhi High Court on Monday directed the Delhi government that if anybody is overcharging and black marketing oxygen cylinders they should be brought before the court, reports ANI.

Justice Vipin Singh said that he earlier today got a call that people were charging Rs one lakh for an oxygen cylinder. The court asked the Delhi government to exercise its power and bring before them those indulged in black marketing so that the person0020can be taken to task.

Senior Advocate Mehra, on the matter of crisis of oxygen tankers in Delhi, informed the court that initiatives for augmentation of tankers and proposal for 18 tankers has been placed and the tankers will come in 3 batches if the Indian Air Force could facilitate the process.

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arrested
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Virar hospital fire probe: Two docs arrested for fire tragedy

by Medically Speaking Team
written by Medically Speaking Team

Mumbai Police arrested the chief executive officer and chief administrative officer of the Virar hospital where 15 Covid patients dies after a fire broke out in the ICU on Friday.

Both of them have been booked under IPC sections 304 (culpable homicide not amounting to murder), 337, 338 (causing hurt by act so rashly or negligently as to endanger human life) and 34 (common intention).

The nurses, ward boys and doctor on duty night when the incident took place are being questioned, said the police officer. They too are named in the FIR. A nurse told the police that as per protocol, they had called Dr Dilip Shah (CEO) and Dr Shailesh Pathak (CAO) after noticing sparks in the AC unit of the ICU. It was Dr Shah and Dr Pathak who called the fire brigade, said police, adding that allegations of the fire brigade being informed of the blaze after a 15-minute delay is being investigated.

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mankind
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Mankind Pharma to donate Rs. 100 crore to families of HCWs and other Covid warriors

by Medically Speaking Team
written by Medically Speaking Team

Mankind Pharma on Monday said it will donate Rs. 100 crore for the families of deceased doctors, police officers, pharmacists and other healthcare workers who have lost their lives serving people during the pandemic.

In a statement, the company said that it plans to start releasing the money with immediate effect and hopes to complete it within three months.

On the initiative, Mankind Pharma MD and Vice Chairman Rajeev Juneja said, being the first line of defence they are highly exposed to this deadly disease. Many have lost their lives fighting the pandemic and protecting us.

“As a homage to them, we have pledged a fund of ₹100 crore to support and care for the families of these lost warriors. This is not our duty, but a debt we owe them. Because they are truly our hope,” he added.

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drug
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Biocon Biologics Abevmy receives approval

by Medically Speaking Team
written by Medically Speaking Team

Biocon Biologics has received approval for its cancer drug Abevmy co-developed with Viatris. Abevmy 100 & 400mg , a biosimilar of Bevacizumab has received marketing authorization approval from the European Commission (EC) following the positive recommendation by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency, said the company in a filing to the stock exchange, reports TOI.

Abevmy is approved for treatment in metastatic colorectal carcinoma, metastatic breast cancer, non small-cell lung carcinoma, glioblastoma, ovarian, cervical and renal cancer as part of a specific regimen.

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covid patients die due to fire
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4 out of 16 Covid patients rescued in fire at Surat hospital dead

by Medically Speaking Team
written by Medically Speaking Team

Surat (Gujarat): 4 out of the 16 critical Covid patients rescued from a fire that broke out in Ayush Hospital’s ICU ward on Sunday night, died on Monday.

The patients were shifted to safer places by the hospital staff before the fire team arrived, said Basant Pareek, In-charge Chief Fire Officer of Surat Municipal Commission (SMC).

The fire broke out after a blast in the air conditioner caused either due to the short circuit or overloading, he said.

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usfda
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Generic meds recalled by US Pharma companies – Sun Pharma, Lupin and Jubilant Cadista

by Medically Speaking Team
written by Medically Speaking Team

As per the latest Enforcement Report by the US Food and Drug Administration (USFDA), the US-based unit of Lupin is recalling 17,814 bottles of Cefprozil for Oral Suspension USP, a second-generation antibiotic used to treat ear infections, skin infections, and other bacterial infections.

According to the USFDA, the company is recalling the affected lot for being “Superpotent”.

The affected lot has been manufactured at Lupin’s Mandideep plant in Madhya Pradesh and distributed in the US by Baltimore-based Lupin Pharmaceuticals Inc, the report stated.

Lupin initiated the Class II voluntary recall across the US and Puerto Rico on March 26 this year.

USFDA further stated that Sun Pharma is recalling 13,834 bottles of diabetes drug Riomet (metformin hydrochloride oral solution) in the US due to “Microbial Contamination of Non-Sterile Product”.

The affected lot has been distributed in the US by New Jersey-based Sun Pharmaceutical Industries Inc.

The company initiated Class II nationwide recall on March 31 this year.

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coronavirus variants
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Remdesivir no magic bullet, should not be administered in mild cases: Dr Guleria

by Medically Speaking Team
written by Medically Speaking Team

Doctor Randeep Guleria, Director of All India Institute of Medical Sciences, Dr. Naresh Trehan, Chairman and Managing Director, Medanta, Dr. Navneet Wig, Head of Department of Medicines, AIIMS and Dr Sunil Kumar, Director General Health Services today addressed concerns and issues related to COVID19.

DrRandeepGuleria, while speaking on the shortage of oxygen and medicines said, “Hoarding of injections like remdesivir and oxygen in homes is creating a panic and this hoarding is causing a shortage of these medicines. COVID19 is mild infection and 85-90% people will only suffer from cold, fever, sore throat and bodyache. Only symptomatic treatment at home is enough to ride through these infections and there is no need for oxygen or remdesivir.” He added that 10-15% percent of patients with severe infections may need oxygen, remdesivir or plasma etc while less than 5% patients need ventilators or intensive care.

Furthermore, Dr Guleria clarified that remdesivir neither reduces the hospital stay nor saves lives. In moderate to severe cases, it may be able to reduce hospital stay but if administered in mild cases it can complicate matters. Remdesivir is no magic bullet and it is used in hospitals for moderate to severe cases.

On administration of oxygen to non-needy, Dr Guleria said that people who have oxygen saturation above 94 do not need oxygen as increase in oxygen saturation beyond this level would not increase oxygen in blood. However, this can cause shortage in supply of oxygen and will reduce access to oxygen for serious cases.

Dr Naresh Trehan while speaking on the steps to be taken immediately after a positive RT-PCR test, said that people should first contact local or family doctors. All the doctors are aware of the protocol to be followed and can recommend courses of medication for patients who should isolate themselves at home. Dr Trehan also advised yoga and pranayam which are helpful in maintaining lung health and added that Pronation is also helpful. Dr. Trehan reiterated the importance of double masking, distancing and hand hygiene and said the mask should seal the air passage around the nose and mouth for proper protection. He also recommended staying away from crowded places.

Speaking on oxygen demand, Dr Trehan said the demand for medical oxygen has suddenly risen in the current crisis and manufacturing facilities are stretched for supplies. Our industries however have the capacity but lack cryo-transportation. Government is actively working on this and the situation will be under control in the next five to seven days.

Dr Sunil Kumar addressed the topic of preparations of the Government to mitigate the situation and said that from no preparedness last year when Covid arrived, the Government ramped up capacity to a unique level very soon. Over 2500 laboratories were created where only one existed before the pandemic. We increased our testing capability to lakhs of tests per day, ramped up tracking and contact tracing and manufacturing of PPE kits et al. Reiterating the importance of getting vaccinated, Dr Sunil said there are negligible side effects of the vaccines and that vaccines and COVID-appropriate behaviour together can break the chain of transmission.

Dr Navneet said that we need to save our healthcare workers who will in-turn save our patients. To save our healthcare workers we need to break the chain and reduce the number of infections. To break the chain is a responsibility of all sections of society but foremost it is the responsibility of the people to undertake COVID-appropriate behaviour.

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world malaria day 2021
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Reaching Zero Malaria Target – WHO celebrates World Malaria Day 2021

by Medically Speaking Team
written by Medically Speaking Team

April 25 is celebrated as World Malaria Day each year and this year the theme has been declared by World Health Day as ‘Reaching the Zero Malaria Target’ and thus WHO and its partners mark this day by celebrating the achievements of countries that are approaching – and achieving – malaria elimination.

They provide inspiration for all nations that are working to stamp out this deadly disease and improve the health and livelihoods of their populations.

Malaria

Malaria is a life threatening disease. It’s typically transmitted through the bite of an infected Anopheles mosquito. Infected mosquitoes carry the Plasmodium parasite. When this mosquito bites you, parasite is released into your bloodstream.

Once the parasites are inside your body, they travel to the liver, where they mature. After several days, the mature parasites enter the bloodstream and begin to infect red blood cells. Within 48 to 72 hours, the parasites inside the red blood cells multiply, causing the infected cells to burst open. The parasites continue to infect red blood cells, resulting in symptoms that occur in cycles that last two to three days at a time.

World Malaria Day History

The idea of World Malaria Day was developed from Africa Malaria Day. The Africa Malaria day is basically an event that has been observed by African governments since 2001, first held in 2008. In 2007, at the 60th session of the World Health Assembly, a meeting sponsored by the World Health Organisation (WHO) proposed that Africa Malaria Day be changed to World Malaria Day.

What causes Malaria?

Malaria is transmitted by blood, so it can also be transmitted through:

  • an organ transplant
  • a transfusion
  • use of shared needles or syringes

Symptoms of Malaria

The symptoms of malaria typically develop within 10 days to 4 weeks following the infection. In some cases, symptoms may not develop for several months. Some malarial parasites can enter the body but will be dormant for long periods of time.

Common symptoms of malaria include:

  • shaking chills that can range from moderate to severe
  • high fever
  • profuse sweating
  • headache
  • nausea
  • vomiting
  • abdominal pain
  • diarrhea
  • anemia
  • muscle pain
  • convulsions
  • coma
  • bloody stools

Diagnosis

Your doctor will be able to diagnose malaria. During your appointment, your doctor will review your health history, including any recent travel to tropical climates. A physical exam will also be performed.

Your doctor will be able to determine if you have an enlarged spleen or liver. If you have symptoms of malaria, your doctor may order additional blood tests to confirm your diagnosis.

These tests will show:

  • whether you have malaria
  • what type of malaria you have
  • if your infection is caused by a parasite that’s resistant to certain types of drugs
  • if the disease has caused anemia
  • if the disease has affected your vital organs

Treatment

Malaria can be a life-threatening condition, especially if you’re infected with the parasite P. falciparum. Treatment for the disease is typically provided in a hospital. Your doctor will prescribe medications based on the type of parasite that you have.

In some instances, the medication prescribed may not clear the infection because of parasite resistance to drugs. If this occurs, your doctor may need to use more than one medication or change medications altogether to treat your condition.

Additionally, certain types of malaria parasites, such as P. vivax and P. ovale, have liver stages where the parasite can live in your body for an extended period of time and reactivate at a later date causing a relapse of the infection.

If you’re found to have one of these types of malaria parasites, you’ll be given a second medication to prevent a relapse in the future.

Medications

The most common antimalarial drugs include:

  • Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug. But in many parts of the world, parasites are resistant to chloroquine, and the drug is no longer an effective treatment.
  • Artemisinin-based combination therapies (ACTs). ACT is a combination of two or more drugs that work against the malaria parasite in different ways. This is usually the preferred treatment for chloroquine-resistant malaria. Examples include artemether-lumefantrine (Coartem) and artesunate-mefloquine.

Other common antimalarial drugs include:

  • Atovaquone-proguanil (Malarone)
  • Quinine sulfate (Qualaquin) with doxycycline (Oracea, Vibramycin, others)
  • Primaquine phosphate
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Remdesivir
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Five arrested for black marketing of fake Remdesivir

by Medically Speaking Team
written by Medically Speaking Team

Indore: Indore police has arrested 5 people for black marketing and selling fake Remdesivir injection on Saturday, reports ANI.

Three out of the five arrested were booked for black marketing of Remdesivir injection while the other two were involved in fake selling of the injection as the anti-viral drug used to cure Covid-19 patients.

“Two cases have been registered involving Remdesivir at the Lasudia police station. In one case, three people were involved in black marketing of this injection. With the help of crime branch, the police arrested Maan Singh, Ankit Bajrang, who were selling the injection for Rs 30,000,” investigating officer Omkar Bharodia told media.

Talking about the case of selling fake Remdesivir, the officer said, “The police arrested Ujjwal and his companion, for selling a glucose-filled injection calling it Remdesivir at the rate of Rs 20,000. They used to get empty Remdesivir vial from the hospitals and fill them with glucose water.”

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