In a world where luxury often provides an escape from hardship, Anant Ambani—youngest son of India’s richest family—is choosing a different path. Literally.
As he approaches his 30th birthday, Anant has taken on a deeply personal and spiritual mission: a 170-kilometer-long padyatra (pilgrimage on foot) from Jamnagar to Dwarka, seeking divine blessings. Walking around 20 kilometers each night for nearly seven hours, Anant is expected to complete his journey by April 8. But this is not just a spiritual quest—it’s a testament to resilience, inner strength, and a lifelong fight against serious health challenges.
Despite growing up under the public eye and immense privilege, Anant’s journey has been anything but easy. Behind his calm demeanor lies a series of chronic health conditions, including a rare hormonal disorder called Cushing syndrome, morbid obesity, thyroid issues, asthma, and a severe lung disease. But rather than being defined by his illnesses, Anant Ambani is redefining them—through discipline, determination, and faith.
WHAT IS CUSHING SYNDROME?
Cushing syndrome, also known as hypercortisolism, is a rare condition where the body produces too much of the stress hormone cortisol. While cortisol plays a crucial role in managing vital functions like blood pressure, blood sugar regulation, inflammation, and metabolism, an excess of it can disrupt nearly every system in the body.
Some of the major effects of high cortisol levels include:
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Elevated heart rate and blood pressure
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Higher blood sugar levels
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Breathing problems
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Muscle weakness and tension
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Increased fat storage in unusual areas of the body
This condition may be caused by natural hormone imbalances or the long-term use of corticosteroid medications (such as those used to treat autoimmune diseases like lupus, rheumatoid arthritis, or chronic asthma).
WHO IS MOST AFFECTED?
Cushing syndrome is relatively rare, affecting 40 to 70 people per million annually. However, certain groups are more vulnerable:
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Children and teenagers
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Adults aged 25 to 50 years
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Women (about 70% of diagnosed cases)
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People who take cortisol-related medications for extended periods
CAN CUSHING SYNDROME BE LIFE-THREATENING?
Yes, it can be—if not diagnosed and treated on time.
Over time, uncontrolled cortisol levels can wreak havoc on the body. The long-term complications include:
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Obesity and rapid weight gain
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Type 2 diabetes and insulin resistance
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Heart disease and high blood pressure
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Weakened bones and increased risk of fractures
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Severe mood disorders like depression and anxiety
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Blood clots in the lungs or legs
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Memory problems and cognitive issues
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Fatigue and extreme muscle weakness
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Delayed wound healing and frequent infections
If left untreated, these health issues can accumulate and lead to life-threatening consequences.
WHAT CAUSES IT?
Cushing syndrome has a number of causes, which may be either internal or external. The primary causes include:
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Long-term use of corticosteroid medications – Common in treatment for chronic illnesses like asthma, arthritis, or lupus.
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Pituitary gland tumors – These benign growths can trigger the overproduction of cortisol. In fact, 8 out of 10 Cushing cases are linked to these tumors.
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Adrenal gland tumors – Located above the kidneys, these glands may start producing excess cortisol.
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Other tumors – Rare cancers of the lung, pancreas, thyroid, or thymus can also indirectly cause the body to produce too much cortisol.
RECOGNISING THE SYMPTOMS
Cushing syndrome can be tricky to diagnose because its symptoms often overlap with those of other illnesses. However, there are some key signs that can help spot the condition:
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Rapid weight gain, especially in the face (moon face), abdomen, and upper back
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A rounded, red face
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Slow-healing wounds or frequent skin infections
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High blood pressure and elevated blood sugar
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Excess facial or body hair (especially in women), or hair loss
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Easy bruising, especially on arms and legs
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Weak muscles, especially in the arms and legs
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Fatigue, dizziness, and blurry vision
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Decreased libido or erectile dysfunction
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Emotional disturbances, such as anxiety or depression
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Diabetes or prediabetes
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Changes in menstrual cycle for women
WHY ANANT AMBANI’S STORY MATTERS
Anant Ambani’s openness about his health struggles has resonated with many across India. Living with multiple chronic conditions since childhood, he has never let them dim his spirit. Over the years, he has undergone intense medical treatments, lifestyle changes, and even spiritual healing to manage his health.
His current 170-kilometer journey is more than a religious undertaking—it’s a personal statement of triumph over adversity. He is not only drawing spiritual strength from his faith, but also serving as a symbol of hope for those silently battling health conditions every day.
Anant’s story is important because it shines a light on rare diseases like Cushing syndrome, which often go undiagnosed or misunderstood. It reminds us that behind every public figure are human struggles, and sometimes, the biggest victories aren’t measured by wealth or fame—but by courage and endurance.
THE ROAD AHEAD
Raising awareness about conditions like Cushing syndrome is crucial. Because of its rarity, many people remain unaware of its existence until it’s too late. If you or someone you know is experiencing symptoms similar to those listed above, it’s essential to seek medical attention early.
While treatment often includes surgery, medication, or radiation to correct hormone imbalances, early diagnosis can significantly improve quality of life and outcomes.
As for Anant Ambani, his journey to Dwarka is not just a walk—it’s a quiet revolution against odds, a testament to inner strength, and a source of inspiration for many.
